Surp and g-patch domain-containing protein 2 go

Yeast twohybrid screens identified two surp domaincontaining u2. Sugp2 surp and gpatch domaincontaining protein 2 mus. Sf4 is a member of the surp family of splicing factors. D111gpatch domaincontaining protein, contains pfam pf01585. Surp and gpatch domain containing 2 hgnc symbol chromosome. By continuing to browse the site you are agreeing to our use of cookies. Mammalian splicing factor sf1 interacts with surp domains of u2 snrnpassociated proteins. An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated rna species identified by northern blot, rtpcr, affinity labeling, sequencing, or microarray analysis. Stress granule wikimili, the best wikipedia reader. Pdf regulation of deahrha helicases by gpatch proteins. Both sf4 and sfrs14 contain 2 surp motifs and a single gpatch domain in. Surp and gpatch domaincontaining protein 1, rnabinding protein rbp, splicing factor 4. Experimental evidence code role dataset throughput curated by notes. Secondary structure prediction indicates that the gpatch domain probably contains two.

Sugp2 surp and gpatch domain containing 2 is a protein coding gene. Alternatively spliced transcript variants have been described. Microarray expression data obtained from different tissues, including leaves, roots and nodules gse18822, seeds during development gse21598 and gse26443 and seedlings treated with salt stress gse41125, were used to evaluate a novel reference gene of soybean, glyma. Experimental evidence code role dataset throughput curated by.

Loc103282934 surp and gpatch domaincontaining protein 2 green anole gene id. Among its related pathways are gene expression and mrna splicing major pathway. If you wish to explore the tree dynamically, please use the go explorer drag and drop nodes to manually position i. Sugp1 surp and gpatch domaincontaining protein 1 homo. Atlas of genetics and cytogenetics in oncology and haematology home genes leukemias solid tumors cancerprone deep insight case reports journals portal teaching. Heat shock 70 kda protein 8 also known as heat shock cognate 71 kda protein or hsc70 or hsp73 is a heat shock protein that in humans is encoded by the hspa8 gene on chromosome 11. Surp and gpatch domaincontaining protein 1, rnabinding protein rbp, splicing factor. Browse our g patch domain and ankyrin repeats 1 proteins. Rank locus id links locus select coexpressed genes description mutual rank weighted pcc wolf psort kegg pathway transcription factor gene symbol gene name msu id. Sensing of alzheimers disease and multiple sclerosis using nanobio interfaces. Lotus base uses cookies to allow user preferences to be stored. Sugp1 surp and gpatch domain containing 1, authors. Gene ontology go annotations related to this gene include nucleic acid.

Mammalian splicing factor sf1 interacts with surp domains of. Mammalian splicing factor sf1 interacts with surp domains of u2. Sugp1, surp and gpatch domain containing 1 orthology source. Go to header go to navigation go to search go to contents go to footer in footer section.

Genomewide analysis of hepatic lipid content in extreme obesity. The rna molecules stored are stalled translation preinitiation complexes. We identified the proteins by mass spectrometry and found that levels of the spliceosomal protein sugp1 surp and gpatch domain containing 1 were greatly reduced in the mutant sf3b1 spliceosome. Several groups of gpatch containing proteins are conserved in animals, plants and fungi. Gtex compendium human tissue compendium novartis global cancer map broad institute nci60 cell lines national cancer institute.

We used affinity purification to isolate spliceosomal complexes associated with either wildtype wt or the hotspot k700e mutant sf3b1. Tm6sf2 is located on chromosome 19 precisely at locus 19p. Go summary ubiquitinrelated, function unknown, cellular component unknown. Loc103282934 surp and gpatch domaincontaining protein 2. Over 90% of the omims operating expenses go to salary support for md and phd science writers and biocurators. The gpatch is a glycinerich domain discovered by sequence alignment, involved in protein protein and protein nucleic acid interaction. Omim entry 614396 gpatch domaincontaining protein 8. This gene encodes a member of the arginineserinerich family of splicing factors. Sf4 and sfrs14, two related putative splicing factors on human chromosome 19p. Surp and gpatch domaincontaining protein 2 sugt1 sugt1 sgt1 homolog, mis12 kinetochore complex assembly cochaperone sun1. Clicking the images or links will redirect you to a website hosted by benchsci that provides thirdparty scientific content. The function of two helicases from this family, prp2 and prp43, is regulated by protein partners containing a gpatch domain.

Sensing of alzheimers disease and multiple sclerosis. A complex component surp and gpatch domaincontaining protein 1. In some of these proteins the g patch is the only recognisable domain but in most of them it is combined with other domains, which include welldefined rnabinding domains, such as the rrm, dsrbd, surp and r3h. Identification of reference genes for quantitative. Q9nw752 fasta add to basket added to basket the sequence of this isoform differs from the canonical sequence as follows.

Pdf on jan 1, 2020, mat jusoh and others published ijhoscr. Recently, it was reported that hotspot mutations in sf3b1 specifically disrupted the interaction with the spliceosomal protein, surp and the gpatch domaincontaining 1 sugp1, without the. Of the genotyped markers, only rs10401969, located in the surp and g patch domain containing 1 sugp1 gene, was nominally associated with fasting tc concentration p 0. Diseases associated with sugp1 include louping ill and osteogenesis imperfecta, type i. Q8ix01 direct mapping surp and gpatch domaincontaining protein 2. Gene ontology go annotations related to this gene include nucleic acid binding and rna binding. Sugp1 surp and g patch domain containing 1, authors.

Liang tj 2010 the association of genetic variability in patatinlike phospholipase domaincontaining protein 3 pnpla3 with histological severity of nonalcoholic fatty liver disease. Sugp2 surp and gpatch domaincontaining protein 2 homo. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool. Two additional proteins containing surp domains were found by coip table table1, 1, the u2 snrnpassociated surp motifcontaining protein u2surpsr140 and the a complex component surp and gpatch domaincontaining protein 1 sugp1sf4. Sensing of alzheimers disease and multiple sclerosis using. Neither the content nor the benchsci technology and processes for selection have been evaluated by us. Loc100555567 surp and gpatch domaincontaining protein 2.

Interpro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. Surp module chlorophyll ab binding protein cp29 lhcb4, identical to cp29 arabidopsis. Loc111143922 surp and gpatch domain containing 2 gene id. Genomewide analysis of hepatic lipid content in extreme.

Sugp2 surp and gpatch domain containing 2 helmeted. Loc100555567 surp and gpatch domaincontaining protein 2 green anole gene id. Niddm29 qtl report rattus norvegicus rat genome database. Oct 12, 2019 sf4 is a member of the surp family of splicing factors. Vset and immunoglobulin domaincontaining protein 10like. Several groups of gpatch containing proteins are conserved in animals. Hitpredict high confidence proteinprotein interactions. The arg59trp variant in angptl8 betatrophin is associated.

Sugp2 protein expression summary the human protein atlas. Comparison of expression stability between a novel soybean reference gene and known reference genes. U2surpsr140 and the a complex component surp and gpatch domaincontaining protein 1 sugp1sf4. G patch domain and ankyrin repeats 1 proteins gpank1 is located in a cluster of hlabassociated transcripts, which is included in the human major histocompatability complex iii region. Surp and gpatch domaincontaining protein 2imported. Diseasecausing mutations in sf3b1 alter splicing by. Sugp1 surp and gpatch domain containing 1 is a protein coding gene. None of the remaining markers showed statistically significant evidence for association with this trait in pima indians. Among its related pathways are mrna splicing major pathway. Stress granules are 100200 nm in size when biochemically purified, not surrounded by membrane, and. Gpatch domain ipr000467 interpro entry interpro emblebi. As we move to using wikipedia as our main source of annotation, the contents of. Ipr040169 surp and gpatch domaincontaining protein 12.

Swap suppressorofwhiteapricotsurp domaincontaining protein, contains pfam domain pf01805. Sugp2 surp and gpatch domain containing 2 helmeted guineafowl gene id. It is flanked by sugp1 a surp and gpatch domaincontaining protein thought to play a role in premrna splicing and hapln4 a hyaluronan and proteoglycan link protein 4 that binds to hyaluronic acid and may be involved in formation of the extracellular matrix genes upstream and downstream respectively. Surp and gpatch domaincontaining protein 2, arginineserinerichsplicing factor 14, splicing factor, arginineserinerich 14. Sugp2 surp and gpatch domain containing 2 homo sapiens. Mammalian splicing factor sf1 interacts with surp domains. Swap suppressorofwhiteapricotsurp domaincontaining protein d111gpatch domaincontaining protein. Oct 12, 2019 the encoded protein functions in mrna processing. Rna helicases from the deahrha family are present in all the processes of rna metabolism. Ontomate literature search jbrowse genome browser variant visualizer multiontology enrichment moet geneortholog location finder golf interviewer protein protein interactions phenominer quatitative phenotypes gene annotator olga gene list generator ratmine gviewer genome viewer overgo probe designer acp haplotyper genome scanner.